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PLAZMAFEREZİS (PLAZMA EXCHANGE)


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Medicine and Hematology Glossary

PLAZMAFEREZİS (PLAZMA EXCHANGE)

(Medicine and Hematology Glossary) :
Patogenezinde dolaşan antikorlar veya antijen/antikor komplekslerinin rol aldığı hastalıkların tedavisinde kullanılır. İşlem otomatik kan ayırıcı araçlarla yapılmaktadır. Hastaya damar yolu açılır ve alete bağlanır. Hastadan kan çekilir, çekilen kandaki serum ve şekilli elemanlar birbirinden ayrılır. Şekilli elemanlar hastaya geri verilir. Alınan serumun yol açacağı volüm kaybı için albümin veya taze donmuş plazma ile replasman yapılır. En etkili olduğu hastalıkların başında myasthenia gravis ve Goodpasture sendromu gelir. Hiperviskozite sendromu, soğuk aglutininlerin oluşturduğu hemolitik anemiler ve esansiyel kriyoglobulinemide de çok etkilidir. Daha az etkili olmak üzere romatoid artrit, diğer vaskülitler, post transfüzyon purpurası, Guillain-Barre sendromu ve multiple skleroziste de kullanılır.
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